2019-Sustainable Industrial Processing Summit
SIPS2019 Volume 15: Oxidative Stress for Sustainable Development of Human Beings

Editors:F. Kongoli, H. Inufusa, C. Amatore, H.Y. Chen, W.H. Huang, T. Yoshikawa
Publisher:Flogen Star OUTREACH
Publication date:20 December 2019
Pages:64 pages
ISBN:978-1-989820-14-8
ISSN:2291-1227 (Metals and Materials Processing in a Clean Environment Series)
CD-SIPS2019_Volume1
CD shopping page

    The Effect of Ginseng on Human Antioxidant Capacity

    Hiroshi Ichikawa1; Yuta Noguchi2; Maryam Shafei2; Chiharu Myo2; Keiko Kobayashi3; Yukiko Minamiyama4; Haruhiko .Inufusa5; Toshikazu Yoshikawa6;
    1DOSHISHA UNIVERSITY, Kyotanabe City, Japan; 2MAJOR OF MEDICAL LIFE SYSTEMS, GRADUATE SCHOOL OF LIFE AND MEDICAL SCIENCES, DOSHISHA UNIVERSITY, Kyotanabe City, Japan; 3KYOTO PREFECTURAL UNIVERSITY, Kyoto, Japan; 4KYOTO PREFECTURAL UNIVERSITY, KYoto, Japan; 5CEO, TIMA/GIFU UNIVERSITY, Osaka, Japan; 6LOUIS PASTEUR CENTER FOR MED. RES., Tohoku, Japan;
    Type of Paper: Regular
    Id Paper: 219
    Topic: 54

    Abstract:

    Ginseng has been reported about for its immunostimulation and its effects on various diseases such as obesity, diabetes and cancer. In this study, from the viewpoint of antioxidant and oxidative stress, the influence of ginseng on humans was examined. By using the MULTIple free-radical Scavenging (MULTIS method), we measured the scavenging activity of the reactive oxygen species: hydroxyl radical (・OH), superoxide radical (O2・-), alkyloxy radical (RO・), alkyl peroxy radical (ROO・), methyl radical (・CH3), and singlet oxygen (1O2). We also evaluated the antioxidant capacity multifaceted.
    On the first day, subjects’ samples (plasma and saliva) were taken before ingesting ginseng tablets (n=5). After that, the samples were taken again, 4 hours after the administration of 18 tablets. They continued taking 18 tablets per day from the second day to the sixth day. On the seventh day, the samples were collected. The antioxidant capacity of the samples was examined using the MULTIS method.
    By ingestion of ginseng tablets, the ・OH scavenging activity of samples increased after 1 week. Also, plasma ・CH3, and saliva O2・- scavenging activity increased. It was suggested that ginseng improved the antioxidant capacity of human.

    Keywords:

    Aging; Bacterial flora;

    References:

    1. Chasing great paths of Helmut Sies "Oxidative Stress".
    Majima HJ, Indo HP, Nakanishi I, Suenaga S, Matsumoto K, Matsui H, Minamiyama Y, Ichikawa H, Yen HC, Hawkins CL, Davies MJ, Ozawa T, St Clair DK
    Archives of biochemistry and biophysics 595 54-60 2016
    2. A mitochondrial superoxide theory for oxidative stress diseases and aging
    Indo Hiroko P., Yen Hsiu-Chuan, Nakanishi Ikuo, Matsumoto Ken-ichiro, Tamura Masato, Nagano Yumiko, Matsui Hirofumi, Gusev Oleg, Cornette Richard, Okuda Takashi, Minamiyama Yukiko, Ichikawa Hiroshi, Suenaga Shigeaki, Oki Misato, Sato Tsuyoshi, Ozawa Toshihiko, St Clair Daret K., Majima Hideyuki J.
    JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 56(1) 1-7 2015

    Cite this article as:

    Ichikawa H, Noguchi Y, Shafei M, Myo C, Kobayashi K, Minamiyama Y, .Inufusa H, Yoshikawa T. (2019). The Effect of Ginseng on Human Antioxidant Capacity. In F. Kongoli, H. Inufusa, C. Amatore, H.Y. Chen, W.H. Huang, T. Yoshikawa (Eds.), Sustainable Industrial Processing Summit SIPS2019 Volume 15: Oxidative Stress for Sustainable Development of Human Beings (pp. 31-32). Montreal, Canada: FLOGEN Star Outreach