2023-Sustainable Industrial Processing Summit
Ozawa Intl. Symp. / Oxidative Stress of Human Beings
| Editors: | F. Kongoli, T. Yoshikawa, H. Inufusa, C. A. Amatore, H-Y. Chen, W-H. Huang, H. Van Goor |
| Publisher: | Flogen Star OUTREACH |
| Publication Year: | 2023 |
| Pages: | 96 pages |
| ISBN: | 978-1-989820-84-1 (CD) |
| ISSN: | 2291-1227 (Metals and Materials Processing in a Clean Environment Series) |
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OLD AGE ODOR AND OXIDATIVE STRESS
HARUHIKO INUFUSA1; Fuhua YANG1; Yoshiaki Harakawa1; Toshikazu Yoshikawa2;1GIFU UNIVERSITY, Gifu, Japan; 2LOUIS PASTEUR MEDICAL RESEARCH CENTER, Kyoto, Japan;
Type of Paper: Regular
Id Paper: 151
Topic: 54
Abstract:
Why does baby smell good while the elderly has a distinctive odor? According to a publication by Shiseido Research Center in 2001(1), 2-nonenal is an unsaturated aldehyde with unpleasant odor caused by oxidative degradation reactions of ω-7 unsaturated fatty acids such as palmitoleic acid and bacenic acid found on the skin surface. This means that age-related oxidative stress is a cause of 2-nonenal. In other words, an increase in oxidative stress due to aging is the cause of age-related odor. We measured the change in age-related odor by reducing oxidative stress. Antioxidant composition Twendee X (TwX) was given who has age related odor for 4 weeks. The portable odor sensor KUNKUN BODY (Konica Minolta) was used for 10 participants to measure aging odor. Seventy-four participants were also monitored questionnaires.
Several participants whose odor KUNKUN BODY scores were 80-100, which dropped scores to zero after 3 weeks. Seventy-two of the 74 cases showed a decrease in age-related odor.
Oxidative stress increases with age and is a cause of many diseases. The development of age-related odors suggests increased oxidative stress. Reduction of age-related odors with the antioxidant composition TwX is suggested not only to reduce bad odors but also to maintain health.
Keywords:
Ageing; Anti-Oxidants; Old Age OdorReferences:
1.Inufusa H. Characterization of cell protection effects of Twendee X by oxidative stress. J World Mitochondria Soc. 2016; 2: 42.2. Haruhiko I. Composition for protection against cytotoxic effects. Tima Foundation. Patent No. 5777821. 2015-9-9.
3. Haze S, Gozu Y, Nakamura S, Kohno Y, Sawano K, Ohta H, Yamazaki K. 2-Nonenal newly found in human body odor tends to increase with aging. J Invest Dermatol. 2001 Apr;116(4):520-4.