2025 - Sustainable Industrial Processing Summit
SIPS2025 Volume 2. Inufusa Intl. Symp. / Oxidative Stress and Technological Innovations in Medicine
| Editors: | F. Kongoli, K. Abe, W. Cho, K. Fukui, S. Hirano, D. Joseph, T. Yoshikawa, J.R. Ribas, N. Tran |
| Publisher: | Flogen Star OUTREACH |
| Publication Year: | 2025 |
| Pages: | 282 pages |
| ISBN: | 978-1-998384-40-2 (CD) |
| ISSN: | 2291-1227 (Metals and Materials Processing in a Clean Environment Series) |
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ALLERGIC AND INFLAMMATORY AIRWAY DISEASES: POTENTIAL INFLUENCE OF OXIDATIVE STRESS
Yuki Sato1; Yoichiro Sugiyama1; Haruhiko Inufusa2; Fuhua Yang2; Davis Joseph2; Shigeru Hirano3;1SAGA UNIVERSITY, Saga, Japan; 2GIFU UNIVERSITY, Gifu, Japan; 3KYOTO PREFECTURAL UNIVERSITY OF MEDICINE, Kyoto, Japan;
Type of Paper: Invited
Id Paper: 158
Topic: 54
Abstract:
The respiratory system is essential for efficient gas exchange in the lungs and for maintaining airway clearance. Various factors, including allergies and inflammation, can adversely impact both respiratory function and the non-respiratory behaviors that protect the airways. Conditions such as asthma and other chronic respiratory diseases increase significant health risks, with an increasing number of cases reported. Moreover, allergic responses and chronic inflammation in the upper and lower airways can trigger excessive reflexes, such as sneezing and coughing, which may exacerbate respiratory conditions.
Research on oxidative stress in chronic airway diseases has demonstrated a correlation between chronic airway inflammation and elevated oxidative stress levels. Increased oxidative stress may affect not only inflammation in peripheral tissues but also the central mechanisms that regulate coughing and sneezing. However, theoretical evidence on this topic remains limited. In this overview, we will outline the clinical features of allergic and inflammatory respiratory diseases, including allergic rhinitis and asthma. We will also highlight the basic peripheral and central mechanisms controlling airway reflexes, including sneezing and coughing.
In addition, we will explore the relationships between respiratory disorders and oxidative stress and propose potential benefits of antioxidants, such as Twendee X®, in alleviating pathogenic respiratory distress and reducing hypersensitivity of airway protective reflexes.