In Honor of Nobel Laureate Dr. Aaron Ciechanover
| SESSION: MedicineTuePM3-R9 |
4th Intl. Symp. on Technological Innovations in Medicine for Sustainable Development |
| Tue. 18 Nov. 2025 / Room: Benjarong Main Rest | |
| Session Chairs: Paata Kervalishvili; Olga Peryanova; Student Monitors: TBA | |
A theoretical and experimental search has been conducted for a model to explain the therapeutic effect of the "Philippine healer" - ultrafast healing of medical wounds. We came to the conclusion that the AIM+ - model is more suitable than the others. Previously [1-3] were presented: FK, DFK, AIM, AIM+ models.
The FK model is an elastic-periodic chain of atoms (CH1) in a periodic potential, which is described by commensurate and incommensurate phases.
In the DFK model, the periodic potential of the FK model is replaced by a second elastically periodic chain of atoms (CH2).
In the AIM model, the cosmological applications of the FK + DFK models are considered, through the creation of a time chain (CH1 + CH2), a type of open system.
The rubaiyat of Omar Khayyam voiced the cosmological idea of the AIM model:
“Oh, woe! Nothingness is embodied in our flesh,
Nothingness is surrounded by a border of celestial spheres.
We tremble in horror from birth to death:
We are ripples on Time, but it is nothing.”
In the AIM+ model, CH1 atoms returning to the jerk point form a cloud of gas, which condenses on the energy excitations of the time chain (CH1+ CH2), forming associated states with them.
Let us call the emerging states “living cells” (LC). LCs can be two-dimensional, three-dimensional, etc. It is possible that the first three-dimensional LC was formed at the stage of inflationary growth of the Universe long before the point of the “Big Bang”; let’s call it “inflaton”.
AIM+ model considers the phase of inflationary growth of the Universe as the initial stage of the development of a microbial colony.
It is known that communities of biological cells are open biological systems, which at the initial stages develop according to an exponential law (I-phase). But then they plateau very quickly. We believe that the I-phase can be extended by creating a coherent state for the LC (CR mode), when the entire community develops coherently.
In experiments [4, 5] the problem of creating one of the possible CR modes in microbiological systems was solved: - stimulating the growth of a colony of a microbiological culture of e.coli with a physical device with spatial coherence, by resonantly matching the size of a biological cell with the coherence period of the device. As a result: - we observed CR stimulated by an external field - modes with single and multiple subcultures of the microbiological culture.
