Hyperthyroidism is a general term for a group of disorders characterized by an excessive secretion of thyroid hormones, which affect many vital bodily functions, leading to an accelerated rate of important bodily processes. The causes include Graves' disease, the most common form, toxic multinodular goiter, and thyroiditis, among others. In all cases, patients with this disorder experience increased oxidative stress in the body, which is known to be deeply involved in the pathogenesis of the disease. Furthermore, mitochondria are a primary target of oxidative stress and may contribute to tissue dysfunction associated with hyperthyroidism.

Twendee X (TwX) is an antioxidant supplement containing vitamins, amino acids, and CoQ10. It has passed pharmaceutical-grade safety tests and previous studies have shown that it reduces oxidative stress and protects mitochondrial function. In a case study of patients with Graves' disease who took TwX, elevated thyroid hormone levels normalized shortly after supplementation. TwX shows promise as a safe, antioxidant-based treatment for hyperthyroidism.