2018 - Sustainable Industrial Processing Summit & Exhibition
4-7 November 2018, Rio Othon Palace, Rio De Janeiro, Brazil
Seven Nobel Laureates have already confirmed their attendance: Prof. Dan Shechtman, Prof. Sir Fraser Stoddart, Prof. Andre Geim, Prof. Thomas Steitz, Prof. Ada Yonath, Prof. Kurt Wüthrich and Prof. Ferid Murad. More than 400 Abstracts Submitted from about 60 Countries.
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    Extraction of Creatinine by Adsorption Onto Pure Micro- and Mesoporous Silica Materials
    Hadj Hamaizi1; Leila Kharbouche2; Ghazala Benbakhta2; Mustapha Mokhtari3; María Dolores Gil García3; María Martínez Galera3;
    1, Oran, Algeria; 2UNIVERSITY OF ORAN, Oran, Algeria; 3UNIVERSITY OF ALMERíA, Almeria, Spain;
    PAPER: 15/Non-ferrous/Regular (Oral)
    SCHEDULED: 17:10/Mon./Pontal (50/2nd)



    ABSTRACT:
    This report describes the compositional and structural design strategy of a micro- and mesoporous silica materials mesh for the efficient removal of uremic toxins towards blood purification application. Our investigation gives the results of the syntheses involving nonionic surfactants and tetraethylorthosilicate (TEOS) as silica precursors for the extraction of urea and creatinine from human blood. The procedure of materials preparation is widely used in the synthesis of mesoporous solids. By using various amounts of non ionic surfactants (Brij S 100 and TRITON X-114) never used before in the synthesis, micro- and mesoporous purely silica samples were obtained. Structural and textural parameters indicated the presence of mesopores interconnected with micropores in a "wormhole-like" or cubic disposition. Adsorption of urea and creatinine, waste biological molecules, onto silica materials was studied and a drastic diminution of creatinine concentration from blood plasma was observed, by a simple contact at ambient temperature. The synthesis protocol, the characterization of materials as well as the results of creatinine adsorption are detailed and a discussion is proposed in this work. Micro- and mesoporous silica are convenient for both research and biomedical applications.

    References:
    [1] P.T. Tanev, T.J. Pinnavaia, Science, 267 (1995) 865-867
    [2] S.A. Bagshaw, E. Prouzet, T.J. Pinnavaia, Science, 269 (1995) 1242-1243
    [3] Y. Cao, Y. Gu, K. Wang, K, J.Taiwan Institute of Chemical Engineers, 66 (2016) 347-356
    [4] R. Takai, R. Kurimoto, Y. Nakagawa, Y. Kotsuchibashi, K. Namekawa, M. Ebara, Journal of Nanomaterials, (2016) http://dx.doi.org/10.1155/2016/5638905.