FLOGEN Star Outreach is proud to recognize a new scientific achievement by Davis Joseph, recipient of the Semenza International Cell Engineering in Medicine Award at SIPS 2024. His latest single-author article, "The Unified Theory of Neurodegeneration Pathogenesis Based on Axon Deamidation," has reached over 600 downloads in just five days, establishing his second major record in the field of neurodegenerative disease research.

Read the article here: https://www.mdpi.com/1422-0067/26/9/4143

The paper outlines a transformative discovery: a unified theory that identifies a common master switch in the pathology of Alzheimer’s, Parkinson’s, and other brain-related diseases. This insight offers the potential for unified, effective therapeutic strategies across multiple neurological conditions.

This success follows Davis Joseph’s previous single-author article, published in the prestigious International Journal of Molecular Sciences (IJMS), a Q1-ranked journal in Biochemistry and Molecular Biology, which has now been accessed more than 8,000 times within just 5.5 months of publication.

Read the article here: https://www.mdpi.com/1422-0067/25/22/12268

For this groundbreaking body of work, Davis Joseph was honoured at FLOGEN’s Sustainable Industrial Processing Summit (SIPS 2024) with the Semenza International Cell Engineering in Medicine Award. The award was presented in person by Prof. Gregg Semenza, Nobel Laureate in Physiology or Medicine (2019), and C. Michael Armstrong Professor of Genetic Medicine at Johns Hopkins University.

Scientific Significance and Context

This publication sets a new standard in multiple dimensions:

• It is a rare and impactful single-author paper: a format increasingly uncommon in modern scientific literature.
• The author not only proposed the theory but also conducted the experimental validation and developed novel scientific methods.
• According to recent data, only 0.43% of all research papers published in 2020 were single-authored. To view the figure click here: https://link.springer.com/article/10.1007/s11192-024-04928-1#Tab3, Fig. 5B and Table 3.
• In contrast, many contemporary papers involve dozens, or even thousands, of co-authors. One such example includes a publication with 5,154 authors.

The impact of Davis Joseph’s work is further underscored by comparison to broader publication trends:

• A 2022 study shows that articles in Q1 journals average 631 views over the first three months. To view the study click here: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019917
• In a review of 320 articles from The Archives of Plastic Surgery (2012–2013), only one paper was accessed more than 199 times. To view the article click here: https://pmc.ncbi.nlm.nih.gov/articles/PMC4037762/).

In contrast, Davis Joseph’s latest article surpassed 600 downloads in just five days, a rate rarely observed in peer-reviewed science publications, especially for single-author contributions.

FLOGEN Star Outreach commends Davis Joseph for this outstanding scientific achievement and his continued commitment to advancing sustainable solutions through innovative research in medicine.